Comparative evaluation of LLMs for patient questions on robotic knee arthroplasty, highlighting their reliability and readability.
BACKGROUND: Robotic-assisted total knee arthroplasty (rTKA) is increasingly used because of its surgical precision. However, inconsistent outcomes and high costs often lead patients to seek additional information from artificial intelligence (AI) tools. Large language models (LLMs) such as ChatGPT-4o, Gemini-2.5-Flash, and DeepSeek-V3 are commonly used, but their reliability and readability in orthopaedics remain unclear. OBJECTIVES: To compare the reliability, usefulness, quality, and readability of responses to common patient questions about rTKA generated by leading LLMs. METHODS: Three LLMs answered 20 frequently asked patient questions (n = 20) identified through Google Trends and expert validation. Three orthopaedic specialists (n = 3) evaluated reliability, usefulness, and overall quality using validated scales, while readability was assessed with standard indices. RESULTS: Inter-rater reliability was good to excellent (ICC = 0.728-0.879). Gemini-2.5-Flash achieved significantly higher reliability and usefulness scores than ChatGPT-4o and DeepSeek-V3 (all p < 0.05). ChatGPT-4o and DeepSeek-V3 produced more readable but less accurate content, revealing an inverse relationship between reliability and readability. CONCLUSIONS: Gemini-2.5-Flash provided the most reliable responses, highlighting the need for supervised integration of LLMs in patient education.
No takes yet. Share an insight, caveat, or question.
Çiftçi et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: