What question did this study set out to answer?

This study assesses how the introduction of biosimilar insulins affects insulin utilization in a tertiary hospital setting.

August 2, 2026International Journal of Healthcare Management

The impact of biosimilar insulin introduction on insulin utilization in a tertiary public hospital in Malaysia: an interrupted time series analysis

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Authors

OFOmotayo Fatokun NHNguyen Thao My Hoang NLNavin Kumar Loganadan

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Overview

Interrupted time series analysis evaluates insulin utilization changes post-biosimilar introduction, indicating significant increases in access and use.

Key Points

This study assesses how the introduction of biosimilar insulins affects insulin utilization in a tertiary hospital setting.
Conducted an interrupted time series analysis using ARIMA modeling on dispensing data from January 2013 to February 2020.
Evaluated utilization changes in isophane and biphasic isophane insulins after the introduction of biosimilars in February 2017.
Isophane insulin utilization increased by 24% (β = 0.213, P = 0.002) post-introduction, then gradually declined.
Biphasic isophane insulin saw an immediate utilization surge of 97% (β = 0.677, P = 0.005) without a significant trend change thereafter.

Cite This Study

Fatokun et al. (2026) studied this question.

synapsesocial.com/papers/6a6eea811b0468a7eeab2ca1 https://doi.org/10.1080/20479700.2026.2709846

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August 2, 2026International Journal of Healthcare Management

The impact of biosimilar insulin introduction on insulin utilization in a tertiary public hospital in Malaysia: an interrupted time series analysis

View Full Paper

Ask AI

Bookmark

Authors

OFOmotayo Fatokun NHNguyen Thao My Hoang NLNavin Kumar Loganadan

Discussion

Member takes

Overview

Interrupted time series analysis evaluates insulin utilization changes post-biosimilar introduction, indicating significant increases in access and use.

Key Points

This study assesses how the introduction of biosimilar insulins affects insulin utilization in a tertiary hospital setting.
Conducted an interrupted time series analysis using ARIMA modeling on dispensing data from January 2013 to February 2020.
Evaluated utilization changes in isophane and biphasic isophane insulins after the introduction of biosimilars in February 2017.
Isophane insulin utilization increased by 24% (β = 0.213, P = 0.002) post-introduction, then gradually declined.
Biphasic isophane insulin saw an immediate utilization surge of 97% (β = 0.677, P = 0.005) without a significant trend change thereafter.

Cite This Study

Fatokun et al. (2026) studied this question.

synapsesocial.com/papers/6a6eea811b0468a7eeab2ca1 https://doi.org/10.1080/20479700.2026.2709846

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