Autoimmune Encephalitis Associated with Multiple Anti-Neuronal Antibodies and Small Cell Lung Cancer

Yoonjeong Na; Jung-Ju Lee; Byung-Kun Kim; Namoh Kim; Michelle Sojung Youn

doi:10.17340/jkna.2026.0013

July 30, 2026Journal of the Korean Neurological AssociationOpen Access

Autoimmune Encephalitis Associated with Multiple Anti-Neuronal Antibodies and Small Cell Lung Cancer

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Key Points

This study aims to explore the connection between autoimmune encephalitis and multiple antineuronal antibodies in the context of small cell lung cancer.
Evaluated cases with acute or subacute consciousness alterations and seizures.
Identified the presence of multiple antineuronal antibodies and paraneoplastic encephalitis.
Analyzed clinical outcomes in relation to autoimmune reactions associated with tumors.
Identified significant association between multiple antineuronal antibodies and small cell lung cancer.
Patients exhibited varying degrees of neurological impairment correlated with antibody presence.
Outcomes indicated a potential necessity for monitoring in at-risk populations with cancer.

Implication

Investigates the association of autoimmune encephalitis with cancer and antibody presence, suggesting clinical implications.

Abstract

급성 혹은 아급성 의식장애와 발작은 뇌염, 독성-대사질환, 뇌졸중, 프라이온 질환 등에서 나타난다.자가면역뇌염(autoimmune encephalitis, AIE)은 신 경세포 표면 및 시냅스 항원에 대한 자가항체에 의한 뇌염으로 정의되며 신생물 딸림뇌염(paraneoplastic encephalitis, PNE)은 종양에 의한 세포내항신경 세포항체와 연관되어 나타난다. 1 PNE에서 다발항신경세포항체(multiple antineuronal antibodies, MAA)가 동반되는 경우는

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Cite This Study

Na et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeaa21b0468a7eeab2e73 https://doi.org/10.17340/jkna.2026.0013

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Autoimmune Encephalitis Associated with Multiple Anti-Neuronal Antibodies and Small Cell Lung Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Autoimmune Encephalitis Associated with Multiple Anti-Neuronal Antibodies and Small Cell Lung Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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