What question did this study set out to answer?

The study aims to determine the prevalence of albuminuria and associated factors in adults with steady-state sickle cell disease in Kinshasa.

August 2, 2026BMC NephrologyOpen Access

Albuminuria and associated renal and hemodynamic factors in adults with steady-state sickle cell disease: a multicenter study with measured GFR

View Full Paper

Ask AI

Bookmark

Authors

YEYannick Mompango EngoleKinshasa General Hospital JBJustine Busanga BukabauUniversity of Kinshasa YNYannick Mayamba NlanduKinshasa General Hospital

Discussion

Member takes

Implication

Multicenter study identifies albuminuria prevalence and associated factors in adults with sickle cell disease, indicating broader healthcare implications.

Key Points

The study aims to determine the prevalence of albuminuria and associated factors in adults with steady-state sickle cell disease in Kinshasa.
Conducted a multicenter cross-sectional study with 279 adults aged ≥ 18 years.
Albuminuria assessed using urinary albumin-to-creatinine ratio and classified per KDIGO categories.
Multivariable linear and logistic regression analyses were performed to identify factors related to albuminuria.
Prevalence of albuminuria was 29.1%, with 21.5% in KDIGO A2 and 7.5% in A3 categories.
Higher pulse wave velocity (β = 2.086, 95% CI: 1.036–3.208; p < 0.001) associated with increased albuminuria.
Urinary α-1 microglobulin ≥ 12 mg/L associated with aOR 3.01 (95% CI 1.80–4.02), indicating significant risk.

Cite This Study

Engole et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeaaf1b0468a7eeab301a https://doi.org/10.1186/s12882-026-05247-8

View Full Paper

Ask AI

Bookmark

Implication

Multicenter study identifies albuminuria prevalence and associated factors in adults with sickle cell disease, indicating broader healthcare implications.

Albuminuria and associated renal and hemodynamic factors in adults with steady-state sickle cell disease: a multicenter study with measured GFR

Discussion

Member takes

Implication

Key Points

Cite This Study

Albuminuria and associated renal and hemodynamic factors in adults with steady-state sickle cell disease: a multicenter study with measured GFR

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider