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July 31, 2026Zeitschrift für Kristallographie - New Crystal StructuresOpen Access

The cocrystal of progesterone – ferulic acid (2/1), C ₅₂ H ₇₀ O ₈

Yu Jie Chen Yimin Hou Huahui Zeng

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Key Points

This research aims to determine the crystallographic structure of the progesterone-ferulic acid cocrystal.
Synthesis of the cocrystal with a 2:1 molar ratio of progesterone to ferulic acid.
Characterization using X-ray diffraction to analyze the crystal structure.
Measurement of unit cell parameters and angles.
Identified the cocrystal molecular formula as C52H70O8.
Determined the triclinic crystal system with specific unit cell dimensions: a = 7.65520 Å, b = 12.0376 Å, c = 14.0162 Å, and angles α = 113.641°, β = 102.8250°, γ = 95.2620°.
Reported a volume of 1129.82 Å3 for the unit cell.

Implication

Crystallographic analysis reveals the cocrystal structure of progesterone and ferulic acid, indicating novel interactions.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeabf1b0468a7eeab322b https://doi.org/10.1515/ncrs-2026-0276

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