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August 2, 2026Journal of Conservative Dentistry and Endodontics

Partial radicular versus coronal pulpotomy using chitosan and platelet-rich fibrin in vital permanent molars with irreversible pulpitis, with or without associated apical periodontitis: A randomized controlled trial

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Authors

NMNeelam MittalHBHarakh Chand BaranwalDSDeepti Singh

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Overview

Randomized trial compares outcomes of pulpotomy techniques in vital permanent molars, suggesting effective alternatives to root canal therapy.

Key Points

  • To evaluate the clinical and radiographic outcomes of coronal versus partial radicular pulpotomy in vital molars with irreversible pulpitis.
  • Randomly assigned 68 patients aged 15–35 with carious exposure to four groups: coronal pulpotomy with chitosan, coronal pulpotomy with PRF, partial radicular pulpotomy with chitosan, and partial radicular pulpotomy with PRF.
  • Procedures followed standardized protocols using Biodentine as the sealing material and assessed postoperative pain with a Visual Analog Scale.
  • Radiographic healing evaluated at 3, 6, and 12 months using intraoral periapical radiographs and cone-beam computed tomography.
  • All groups exhibited a significant reduction in postoperative pain and demonstrated radiographic healing.
  • Overall 12-month survival rate was 88.2%, highest in the partial radicular pulpotomy with PRF group at 94.1%, with no statistically significant difference (P > 0.05).
  • Both pulpotomy methods showed favorable outcomes, indicating potential as minimally invasive alternatives to conventional root canal therapy.

Cite This Study

Mittal et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeb011b0468a7eeab3bb3https://doi.org/10.4103/jcde.jcde_355_26
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative evaluation of dual-cure resin (TheraCal PT) and Biodentine in coronal pulpotomy of patients with symptoms indicative of irreversible pulpitis: A randomized clinical trial2024 · 7 citations
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  3. 3Discrete pulp canal calcification in a case of full pulpotomy: A 2-year follow-up case report2024
  4. 4Chitosan-Based Antibacterial Bioceramic Materials for Dental Pulp Capping2025
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