Letter reports distinct microbiological changes in spontaneous bacterial peritonitis due to proton pump inhibitors, suggesting important implications for treatment.
To the Editor, We read with great interest the study by Kitchen and colleagues [1] who showed that exposure to proton pump inhibitors (PPIs) is associated with a distinct microbiological profile in culture-positive spontaneous bacterial peritonitis (SBP).In this study, PPI-exposed patients had a markedly higher prevalence of Gram-positive isolates, particularly Enterococcus spp., Streptococcus spp., and Staphylococcus aureus.
No takes yet. Share an insight, caveat, or question.
SIMEONI et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: