What question did this study set out to answer?

Identify prevalence of herb-drug interactions and disclosure rates of herbal medicine use among patients with NCDs.

August 2, 2026PLoS ONEOpen Access

Herbal medicine use disclosure, database-flagged potential herb-drug interactions, and inter – interaction database concordance among patients with non-communicable diseases in Vietnam: A multicenter cross-sectional study

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Identify prevalence of herb-drug interactions and disclosure rates of herbal medicine use among patients with NCDs.
Observational study of 658 patients with NCDs from two Vietnamese tertiary care facilities.
Structured interviews assessed herbal medicine use patterns and disclosure practices.
Potential interactions evaluated using four drug interaction databases.
48.6% of participants reported herbal medicine use; 96% did not disclose this to healthcare providers.
Potential interactions found in 31.3% of herbal users, representing 15.2% of total patients.
Only 0.7% of interactions were consistently documented across all databases (Fleiss’ κ = –0.0653; p < 0.001).

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Implication

Cross-sectional study reveals high herbal medicine use and poor database concordance among patients with NCDs, indicating risks for medication safety.

Cite This Study

Phan et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeb2c1b0468a7eeab41d7 https://doi.org/10.1371/journal.pone.0355046

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Implication

Cross-sectional study reveals high herbal medicine use and poor database concordance among patients with NCDs, indicating risks for medication safety.

Herbal medicine use disclosure, database-flagged potential herb-drug interactions, and inter – interaction database concordance among patients with non-communicable diseases in Vietnam: A multicenter cross-sectional study

Key Points

Discussion

Implication

Cite This Study

Herbal medicine use disclosure, database-flagged potential herb-drug interactions, and inter – interaction database concordance among patients with non-communicable diseases in Vietnam: A multicenter cross-sectional study

Key Points

Discussion

Implication

Cite This Study

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