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August 2, 2026Current Epidemiology ReportsOpen Access

Sleep and Circadian Disruption as Contributors to Early Cardiometabolic Vulnerability Among Shift-Working Healthcare Professionals: A Systematic Review

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Authors

SMSalahuddin MohammedNotre Dame of Maryland UniversitySASultan AlDhabeiNajran UniversityAUAleem UnissaUniversity of Illinois at Springfield

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Implication

Systematic review explores how sleep and circadian disruptions impact cardiometabolic health in shift-working healthcare professionals, suggesting early detection methods.

Key Points

  • This review aims to examine the links between sleep, circadian disruption, and early cardiometabolic dysfunction in shift-working healthcare professionals.
  • Systematic review of studies examining sleep quality, circadian misalignment, and related health metrics in shift workers.
  • Assessment of physiological abnormalities including heart rate variability and cortisol levels linked to shift work.
  • Consideration of various factors such as sex, chronotype, and stress affecting physiological susceptibility.
  • All studies found associations between poor sleep quality and reduced metabolic profiles among shift workers.
  • Notable abnormalities identified include issues with heart rate variability and glucose dysregulation linked to night shifts.
  • Emerging monitoring methods may aid in early diagnosis of cardiometabolic risk before major health issues arise.

Cite This Study

Mohammed et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeb2c1b0468a7eeab4202https://doi.org/10.1007/s40471-026-00402-z
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