What question did this study set out to answer?

This research aims to explore the relationship between serum NEFA concentrations and milk production traits during early lactation in Holstein dairy cows.

August 2, 2026BMC Veterinary ResearchOpen Access

Metabolic biomarkers and milk production indicators associated with elevated non-esterified fatty acids in holstein dairy cows

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Authors

SGSamanta GrigėLithuanian University of Health Sciences AGAkvilė GirdauskaitėLithuanian University of Health Sciences ISInga SabeckienėLithuanian University of Health Sciences

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Implication

Observational study evaluates milk production and blood biomarkers in dairy cows with elevated NEFA, indicating metabolic challenges.

Key Points

This research aims to explore the relationship between serum NEFA concentrations and milk production traits during early lactation in Holstein dairy cows.
182 multiparous Holstein cows were enrolled based on NEFA levels, classified as low-NEFA (≤ 0.56 mmol/L) and high-NEFA (> 0.56 mmol/L).
Blood and milk samples were collected simultaneously on early lactation days.
Associations between NEFA concentrations and milk as well as biochemical indicators were analyzed using Spearman correlation and ROC analysis.
Cows with elevated NEFA had significantly higher milk fat and fat-to-protein ratio, along with increased AST, CREA, and sodium (Na) levels (p < 0.05).
Negative correlations were found between NEFA and magnesium (Mg), urea, milk temperature, and gamma-glutamyl transferase (GGT) activity.
Milk fat, CREA, Na, FPR, Mg, and AST effectively differentiated between low and high NEFA cows based on ROC analysis.

Cite This Study

Grigė et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeb2c1b0468a7eeab42b0 https://doi.org/10.1186/s12917-026-05789-x

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Metabolic biomarkers and milk production indicators associated with elevated non-esterified fatty acids in holstein dairy cows

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Cite This Study

Metabolic biomarkers and milk production indicators associated with elevated non-esterified fatty acids in holstein dairy cows

Discussion

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Implication

Key Points

Cite This Study

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