Glaucoma treatment: by the highest level of evidence

50 years ago, ophthalmologists thought glaucoma and increased intraocular pressure to be synonymous.1 In 1958, Wolfgang Leydhecker defined healthy limits for intraocular pressure1 and patients with intraocular pressure of 21 mm Hg or higher received a diagnosis of glaucoma, irrespective of whether there were any signs of glaucomatous damage. They were given intraocular-pressure-lowering eye drops, and were told to use these drops three to four times a day or they would go blind. Patients with pressures of 20 mm Hg or lower were told that they did not have glaucoma.