Key result
An increased anticholinergic burden is linked with low physical function and poor quality of life in frail older persons, highlighting the need for medication review and deprescribing.
Why the study?
Does an increased anticholinergic burden reduce physical function and quality of life in frail older persons?
Does an increased anticholinergic burden reduce physical function and quality of life in frail older persons?
Increased anticholinergic burden is associated with reduced physical function and quality of life in frail older adults, emphasizing the importance of medication review and deprescribing.
The significant impact that some classes of drugs may have on older and frail people is nowadays an emerging issue. In particular, anticholinergics play a central role in this field. The systematic review and meta-analysis conducted by Stewart and colleagues, in accordance with the emerging literature on this topic, clearly demonstrate that an increased anticholinergic burden seems linked with low physical function and poor quality of life. This result underlines the well-established need of medication review, reconciliation, and a deprescribing activity during the clinical assessment of the older person.
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Sanchini et al. (2020) conducted an editorial in Frail older persons. Increased anticholinergic burden was evaluated on Low physical function and poor quality of life. An increased anticholinergic burden is linked with low physical function and poor quality of life in frail older persons, highlighting the need for medication review and deprescribing.
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