Key result
Low birth weight was associated with differences in systolic blood pressure compared to normal birth weight.
Why the study?
Findings on the correlation between birth weight and essential hypertension in children have been conflicting.
Is low birth weight associated with primary hypertension or altered blood pressure in children?
Meta-Analysis
Is low birth weight associated with primary hypertension or altered blood pressure in children?
Answers are grounded in this paper and cite their sources.
This meta-analysis suggests a significant association between low birth weight and altered systolic and diastolic blood pressure in children, with differences noted between pre-term and full-term infants.
BACKGROUND: The purpose of this study was to evaluate of the study the role of LBW on EH in children and by studying the existing published literature. MATERIALS AND METHODS: A comprehensive literature search for original studies was conducted in Clarivate Analytics Web of Science, PubMed, Scopus, and Embase until July 2019. The search used all of the main keywords and its synonyms include essential hypertension, primary hypertension, essential arterial hypertension, idiopathic hypertension, spontaneous hypertension; child, childhood, children, pediatric, pediatrics, infant, infancy, newborn, neonatal, adolescence, teenagers; and BW, newborn weight, neonatal weight, BW. RESULTS: Twelve articles were eligible for the final evaluation. Due to the difference among studies in the report, studies were divided into two-part. The first part, articles were reported in the LBW and NBW groups (interested outcome were SBP and DBP), and the second part was composed as the EH and NR groups (interested outcome were LBW and NBW). In the first part, SMD for SBP was -1.09 with 95% CI (-1.91,-0.26), and was statistically significant (Z=2.58, P=0.010). As well, SMD for DBP was -0.68 with 95% CI (-1.32,-0.05) statistically significant (Z=2.10, P=0.036). In the second part, SMD for SBP was 0.77 with 95% CI (-0.85, 2.39), and was statistically significant (Z=0.93, P=0.352). Subgroup analysis was performed on the pre-term and full- term babies. SMD for SBP was -0.08 with 95% CI (-0.51, 0.35) in the pre-term, and the full-term was -2.07 with 95% CI (-3.47, -0.67). As well, SMD for DBP was -0.02 with 95% CI (-0.20, 0.17) in the preterm, and the term was -1.35 with 95% CI (-1.57, -1.13). CONCLUSION: Although findings of the correlation between BW and EHTN have conflicted. To our knowledge, this is the first report that attempts to a conclusion.
No takes yet. Share an insight, caveat, or question.
Sabri et al. (2021) conducted a meta-analysis in Primary hypertension. Low birth weight vs. Normal birth weight was evaluated on Systolic blood pressure (SBP) (SMD -1.09, 95% CI -1.91, -0.26, p=0.010). Low birth weight was associated with differences in systolic blood pressure compared to normal birth weight.
Synapse has enriched 10 related papers. Consider them for comparative context: