Key result
Gastric pouch resizing for recurrent weight gain after primary Roux-en-Y gastric bypass stabilized weight and resolved obesity-associated comorbidities in 52.9% of patients.
Why the study?
Recurrent weight gain occurs in up to 40% of patients after Roux-en-Y gastric bypass, prompting the need to analyze the effects of gastric pouch resizing on weight loss, comorbidities, safety, and patient satisfaction.
Does gastric pouch resizing improve weight loss and resolve comorbidities in patients with recurrent weight gain after Roux-en-Y gastric bypass?
Cohort (n=48)
No
Does gastric pouch resizing improve weight loss and resolve comorbidities in patients with recurrent weight gain after Roux-en-Y gastric bypass?
p-value: p=<0.05
Gastric pouch resizing is a safe and effective secondary surgical option for weight stabilization and comorbidity resolution in patients with recurrent weight gain after Roux-en-Y gastric bypass.
May support pouch resizing for post-RYGB weight regain; leaves open need for RCTs to confirm benefit.
INTRODUCTION: The most effective treatment for obesity and associated comorbidities is metabolic-bariatric surgery (MBS). Nevertheless, recurrent weight gain is reported in up to 40% of patients after Roux-en-Y gastric bypass (RYGB), eventually with a recurrence of obesity-associated comorbidities. Gastric pouch resizing (GPR) is performed as a low-risk secondary surgery to cease weight regain. We herewith analyzed the effect of GPR after primary RYGB on long-term weight loss, course of comorbidities, safety, and patient satisfaction. METHODS: Forty-eight patients undergoing GPR between 2016 and 2020 at the University Hospital of Zurich were included. Data were collected from a prospective database. GPR was performed laparoscopically and included a resection of the enlarged gastric pouch and a redo of the gastrojejunostomy. Additionally, 37 patients participated in a survey to evaluate PROMs (patient-reported outcome measures). RESULTS: , respectively. Obesity-associated comorbidities were resolved in 53% of patients at follow-up (p < 0.05). Minor postoperative complications occurred in 12.5% while major complications occurred in 10.4% of patients. The PROMs showed high levels of satisfaction after GPR. CONCLUSION: GPR for recurrent weight gain after primary RYGB is a safe procedure resulting in weight stabilization and resolution of obesity-associated comorbidities. It is thus a valuable surgical option in well-selected patients.
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Hehl et al. (2024) conducted a cohort in Recurrent weight gain after Roux-en-Y gastric bypass (n=48). Gastric pouch resizing (GPR) was evaluated on Resolution of obesity-associated comorbidities (p=<0.05). Gastric pouch resizing for recurrent weight gain after primary Roux-en-Y gastric bypass stabilized weight and resolved obesity-associated comorbidities in 52.9% of patients.
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