Key result
Antigen Leu-19 is specifically expressed on satellite cells, myotubes, and fibrillar structures in areas of muscle repair, serving as a molecular marker of human skeletal muscle regeneration.
Population
Human skeletal muscle (normal and diseased) and cultured muscle cells
Design
Preclinical
Authors
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May aid satellite cell studies in muscle repair; leaves open validation for therapeutic applications.
Observational (n=11)
Leu19-Ag serves as a molecular marker for human skeletal muscle regeneration, allowing visualization of repair details using laser scan microscopy.
Schubert et al. (1989) conducted an observational in Muscle regeneration in normal and diseased skeletal muscle (n=11). Muscle regeneration and disease vs. Normal, non-regenerating muscle fibers was evaluated on Localization and expression of Leu-19 antigen in skeletal muscle structures. Antigen Leu-19 is specifically expressed on satellite cells, myotubes, and fibrillar structures in areas of muscle repair, serving as a molecular marker of human skeletal muscle regeneration.
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