Key result
This review explores the impact of antithrombotic drugs, especially anticoagulants, on long-term clinical outcomes following successful transcatheter aortic valve implantation.
Why the study?
Antithrombotic therapy after TAVI balances thrombotic and bleeding risks, but guideline recommendations are driven by expert opinion, and the optimal post-TAVI regimen remains undetermined.
What is the optimal antithrombotic regimen following successful TAVI to prevent thrombotic complications without excessively increasing bleeding risk?
What is the optimal antithrombotic regimen following successful TAVI to prevent thrombotic complications without excessively increasing bleeding risk?
The optimal antithrombotic regimen following TAVI remains undetermined, with current guidelines relying on expert opinion pending results from ongoing randomized trials.
Answers are grounded in this paper and cite their sources.
Post-TAVI antithrombotic regimens remain undetermined; leaves open optimal balance of thrombosis prevention versus bleeding pending randomized trials.
Transcatheter aortic valve implantation (TAVI) is the standard of care for symptomatic severe aortic stenosis. Antithrombotic therapy is required after TAVI to prevent thrombotic complications but it increases the risk of bleeding events. Current clinical guidelines are mostly driven by expert opinion and therefore yield low-grade recommendations. The optimal antithrombotic regimen following TAVI has yet to be determined and several randomised controlled trials assessing this issue are ongoing. The purpose of this article is to critically explore the impact of antithrombotic drugs, especially anticoagulants, on long-term clinical outcomes following successful TAVI.
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Greco et al. (2020) conducted a review in Symptomatic severe aortic stenosis. Antithrombotic drugs (especially anticoagulants) was evaluated. This review explores the impact of antithrombotic drugs, especially anticoagulants, on long-term clinical outcomes following successful transcatheter aortic valve implantation.
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