Key result
Over 2 weeks to 15 years of follow-up, right ventricular systolic pressure rose in 24 of 35 children with pulmonary stenosis due to inadequate growth of the pulmonary valve orifice.
Why the study?
How do hemodynamic parameters and valve orifice area change over time in children with pulmonary stenosis?
Population
35 children with pulmonary stenosis, initially catheterized from 1 day to 9 years of age.
Design
Cohort
Follow-up
2 weeks to 15 years
Authors
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May support serial RVSP monitoring in children with pulmonary stenosis; leaves open optimal intervention timing.
Observational (n=35)
How do hemodynamic parameters and valve orifice area change over time in children with pulmonary stenosis?
In children with pulmonary stenosis, right ventricular systolic pressure often increases over time because the pulmonary valve orifice fails to grow proportionally with stroke volume.
Danilowicz et al. (1975) conducted an observational in Pulmonary stenosis (n=35). Aging / Time was evaluated on Change in right ventricular systolic pressure and pulmonary valve orifice area. Over 2 weeks to 15 years of follow-up, right ventricular systolic pressure rose in 24 of 35 children with pulmonary stenosis due to inadequate growth of the pulmonary valve orifice.
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