Key result
Quisqualate and kainate activate distinct cation-permeable channels in mouse central neurones with multiple conductance states, including an 8 pS channel for quisqualate and a 4 pS channel for kainate.
Population
Mouse central neurones in culture
Design
Preclinical
Authors
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Defines cation permeability of quisqualate/kainate channels in cultured neurones; leaves open roles in synaptic transmission in vivo.
Quisqualate and kainate activate distinct cation-permeable channels with different conductances and kinetics in mouse central neurones.
Ascher et al. (1988) studied Mouse central neurones in culture. Quisqualate and kainate was evaluated on Channel conductance and current characteristics. Quisqualate and kainate activate distinct cation-permeable channels in mouse central neurones with multiple conductance states, including an 8 pS channel for quisqualate and a 4 pS channel for kainate.
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