Key result
Effective orthostatic hypotension and autonomic failure management requires subtype identification and comprehensive treatment.
Why the study?
Orthostatic hypotension may occur as a primary autonomic disturbance or secondary to another condition, and successful management requires identifying the subtype and pursuing a comprehensive treatment plan.
Provides a concise clinical guide emphasizing subtype identification and comprehensive management for patients with orthostatic hypotension and autonomic failure.
Answers are grounded in this paper and cite their sources.
May aid clinicians seeking a concise orthostatic hypotension reference; leaves open the need for prospective trials on management strategies.
Orthostatic hypotension may occur either as a primary disturbance of the autonomic nervous system or as the consequence of another condition. Successful treatment involves identi-fying the subtype and pursuing a comprehensive treatment plan. Dedication This paper is dedicated to Barbara Straus MD, mother, wife, physician, soul mate, and source of all inspiration-BPG. Disclosure The authors report no confl icts of interest. References [1] Wieling, W. and VanLieshout, J.J. 1997. Maintenance of postural normotension in humans. In: Low P (ed) Clinical Autonomic Disorders. Philadelphia PA. Lippincott-Raven , 73–82.[2] Thompson, W.O., Thompson, P.K. and Dailey, M.E. 1988. The effect of upright posture on the composition and volume of the blood in man. T Clin. Invest ., 5:573–609.[3] Shepherd, R. and Shepherd, J.T. 1999. Control of the blood pressure and circulation in man. In: Mathias C. Bannister R. (eds) Autonomic Failure: A textbook of clinical Disorders of the Autonomic Nervous System, (4th edition) Oxford UK, Oxford University Press, 72–5.[4] Joyner, M. and Shepherd, T. 1997. Autonomic regulation of the circulation in Low P (ed.) Clinical Autonomic Disorders (2nd ed)
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Grubb et al. (2008) conducted a review in Orthostatic hypotension and autonomic failure. Comprehensive subtype-directed treatment plan was evaluated. Successful management of orthostatic hypotension and autonomic failure requires identifying the specific subtype and pursuing a comprehensive treatment plan.
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