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The study aims to create a detailed physical map of the Saccharomyces cerevisiae genome.

April 1, 1991GeneticsOpen Access

Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution.

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The study aims to create a detailed physical map of the Saccharomyces cerevisiae genome.
Mapped sites for SfiI and NotI restriction endonucleases recognizing 8-bp sequences.
Used DNA-DNA hybridization probes for genetically mapped genes to construct the physical map.
Identified 131 physical landmarks across the non-rDNA component of the genome.
The map contains 32 chromosome ends, 61 SfiI sites, and 38 NotI sites.
Landmarks suggest genes are uniformly distributed over the yeast genome's physical extent.
The map can be used for mapping genes that have single-copy DNA-DNA hybridization probes.

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Physical map reveals genome organization in Saccharomyces cerevisiae, suggesting uniform gene distribution.

Link et al. (1991) studied this question.

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