Key result
Antihypertensive treatment regimens, particularly those including angiotensin-converting enzyme inhibitors, help slow progressive renal failure in patients with hypertensive renal disease.
Why the study?
What are the current strategies for managing hypertensive renal disease to slow progressive renal failure?
What are the current strategies for managing hypertensive renal disease to slow progressive renal failure?
Strict blood pressure control and the use of ACE inhibitors are recommended to slow the progression of hypertensive renal disease.
BP targets ≤130/85 mm Hg may curb hypertensive ESRD; leaves open 120/75 mm Hg benefit in African Americans.
The incidence of hypertensive end-stage renal disease continues to increase annually. To reduce this incidence, it is necessary to control systolic and diastolic hypertension. Reversible causes should always be sought in any hypertensive patient who develops renal insufficiency. Blood pressure should be reduced to 130/85 mm Hg, and in African Americans with hypertensive renal failure, reducing the blood pressure to 120/75 mm Hg may be beneficial. Any antihypertensive treatment regimen that effectively lowers blood pressure will help slow progressive renal failure. Whenever possible, an angiotensin-converting enzyme inhibitor should be part of the treatment, since these drugs have been shown to be renoprotective beyond their antihypertensive effect in certain renal disease categories.
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Moore et al. (1999) conducted a review in Hypertensive Renal Disease. Antihypertensive treatment and angiotensin-converting enzyme inhibitors was evaluated. Antihypertensive treatment regimens, particularly those including angiotensin-converting enzyme inhibitors, help slow progressive renal failure in patients with hypertensive renal disease.
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