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This paper reviews the evidence regarding the cardioprotective effects of oestrogen replacement therapy in postmenopausal women. Oestrogens have been shown to improve serum lipid profiles, carbohydrate metabolism, and insulin sensitivity; prevent the formation and development of atherosclerotic plaque; reduce blood pressure and plasma fibrinogen levels; and favourably affect overall cardiac function. Thus, oestrogen replacement therapy may prevent or inhibit the progression of existing coronary disease, and may also have a protective effect against acute cardiovascular and cerebrovascular ischaemic events.
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Rosano et al. (1996) conducted a review in Coronary disease and cardiovascular ischaemic events. Oestrogen replacement therapy was evaluated.
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