Key result
Quantitative ST-segment depression predicted cardiovascular death in women, but this prognostic effect disappeared when women with left ventricular hypertrophy were excluded.
Why the study?
Do quantitative measures of ST-segment depression and T-wave amplitude predict cardiovascular mortality in a general population?
Cohort (n=5,613)
Do quantitative measures of ST-segment depression and T-wave amplitude predict cardiovascular mortality in a general population?
Quantitative ST-segment depression predicts cardiovascular death in women in a general population, but this prognostic value is largely driven by the presence of left ventricular hypertrophy.
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May refine gender-specific risk stratification in community cohorts; leaves open prospective validation before clinical adoption.
Anttila et al. (2010) conducted a cohort in General population (n=5,613). Quantitative ST-segment depression and T-wave amplitude was evaluated on Cardiovascular mortality. Quantitative ST-segment depression predicted cardiovascular death in women, but this prognostic effect disappeared when women with left ventricular hypertrophy were excluded.
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