Key result
Heparin therapy shows little early clot resolution in major pulmonary embolism.
Observational (n=9)
Answers are grounded in this paper and cite their sources.
Nine patients with major pulmonary embolism who were free of serious cardiopulmonary disease were studied by pulmonary angiocardiography with measurement of pulmonary arterial pressure and cardiac output. The pulmonary angiogram was initially performed 20-0 hours (range 5 to 48 hours) after the first symptoms of the most recent episode of embolism and then repeated after 26A5 hours (range I7 to 48 hours) of heparin therapy. Six patients showed no change, 2 slight improvement, and I deterioration. The reductions in the average values of both the total pulmonary resistance and the mean pulmonary arterial pressure were slight. It was concluded that little resolution of major pulmonary embolism occurs during thefirst 24 to 48 hours of heparin therapy.
No takes yet. Share an insight, caveat, or question.
McDonald et al. (1971) conducted an observational in Major pulmonary embolism (n=9). Heparin therapy was evaluated on Resolution of pulmonary embolism (angiographic and haemodynamic changes). Heparin therapy resulted in little resolution of major pulmonary embolism during the first 24 to 48 hours, with 6 of 9 patients showing no angiographic change.
Synapse has enriched 10 related papers. Consider them for comparative context: