Key result
Non-dialysis-dependent renal dysfunction was independently associated with significantly increased mid-term mortality following coronary artery bypass surgery (adjusted HR 2.7; 95% CI 2.1-3.5; P<0.001).
Why the study?
Does non-dialysis-dependent renal dysfunction increase mortality and morbidity in patients undergoing isolated CABG?
Population
19,558 consecutive patients undergoing isolated coronary artery bypass graft surgery, excluding 67 patients…
Comparison
Non-dialysis-dependent renal dysfunction… vs No history of renal dysfunction.
Design
Cohort
Follow-up
mean 3.0 years
Authors
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Rising renal dysfunction in CABG patients warrants perioperative caution; leaves open optimal management strategies.
Cohort (n=19,625)
Yes
Does non-dialysis-dependent renal dysfunction increase mortality and morbidity in patients undergoing isolated CABG?
Hazard Ratio: 2.7 (95% CI 2.1–3.5)
p-value: p=<0.001
Non-dialysis-dependent renal dysfunction is associated with a significantly increased risk of in-hospital and mid-term mortality and morbidity following CABG.
Devbhandari et al. (2006) conducted a cohort in Coronary artery disease requiring CABG (n=19,625). Non-dialysis-dependent renal dysfunction (NDRD) vs. No history of renal dysfunction (preoperative serum creatinine < 200 μmol/L) was evaluated on Mid-term mortality (HR 2.7, 95% CI 2.1-3.5, p=<0.001). Non-dialysis-dependent renal dysfunction was independently associated with significantly increased mid-term mortality following coronary artery bypass surgery (adjusted HR 2.7; 95% CI 2.1-3.5; P<0.001).
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