Key result
Chronic kidney disease independently increased the risk of major adverse cardiac and cerebrovascular events (HR 1.56) and all-cause death (HR 1.85) in patients with atrial fibrillation undergoing coronary stenting.
Why the study?
Does chronic kidney disease worsen long-term clinical outcomes in patients with nonvalvular atrial fibrillation undergoing coronary stenting?
Observational (n=2,511)
Yes
Does chronic kidney disease worsen long-term clinical outcomes in patients with nonvalvular atrial fibrillation undergoing coronary stenting?
Hazard Ratio: 1.56 (95% CI 1.25–1.96)
Absolute Event Rate: 28.2% vs 14.7%
p-value: p=<0.001
Chronic kidney disease is an independent predictor of all-cause death, MACCE, and major bleeding in patients with atrial fibrillation undergoing coronary stenting.
The effect of chronic kidney disease (CKD) on the long-term prognosis of patients with atrial fibrillation (AF) undergoing coronary stenting was less studied.
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Yongjian Wu (2018) conducted an observational in Nonvalvular atrial fibrillation undergoing coronary stenting (n=2,511). Chronic kidney disease vs. Preserved renal function was evaluated on Major adverse cardiac/cerebrovascular events (MACCE) (HR 1.56, 95% CI 1.25-1.96, p=<0.001). Chronic kidney disease independently increased the risk of major adverse cardiac and cerebrovascular events (HR 1.56) and all-cause death (HR 1.85) in patients with atrial fibrillation undergoing coronary stenting.
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