The First Stable Diazonium Ion on Solid Support—Investigations on Stability and Usage as Linker and Scavenger in Solid-Phase Organic Synthesis

Stability instead of explosiveness characterizes a novel diazonium ion T2* on a solid support, which opens a facile route to the versatile chemistry of diazo compounds and triazenes. This diazonium ion can be used as a linker for the immobilization and modification of amines (see scheme). The high stability also allows its application as a scavenger for amines, anilines, and phenols in combinatorial synthesis in the liquid phase.