Answers are grounded in this paper and cite their sources.
In vitro study demonstrates broad-spectrum fungal inhibition by synthetic fused triazines against pathogenic strains, suggesting their therapeutic potential as novel antifungal candidates.
The preparation and biological activities of a series of pyrido[3,4-e]-1,2,4-triazines, 1,2,4-triazino[5,6-c]quinolines, and related fused triazines are described. Methyl, amino, and acylamino substituents were placed in the pyridyl ring of the former system. Other structural modifications included various alkyl, cycloalkyl, substituted phenyl, and heterocyclic groups in the 3-position of these ring systems. In agar dilution assays, actives in this series inhibited strains of Candida, Aspergillus, Mucor, and Trychophyton species at MIC's of less than or equal to 16 micrograms/mL.
No takes yet. Share an insight, caveat, or question.
Reich et al. (1989) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: