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September 10, 2025Heterocyclic CommunicationsOpen Access

Synthesis of novel triazole hybrids with pyrene, fluorene, and biphenyl groups and evaluation of their antimycobacterial activity

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Authors

AGAkshi GoyalMBM. M. Bhandari

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Overview

Novel triazole compounds display antibacterial and antifungal properties, highlighting potential pharmacophores.

Key Points

  • The novel triazole hybrids exhibit significant antibacterial activity, particularly compounds 1c and 2a.
  • Yields of the synthesized compounds range from fair to good, utilizing azide-alkyne click chemistry techniques.
  • Compounds 2b and 3a demonstrate promising antifungal properties, suggesting their potential as antifungal agents.
  • Solubility tests reveal that the compounds are manageable in ethanol and ethyl acetate solvents.

Cite This Study

Goyal et al. (2025) studied this question.

synapsesocial.com/papers/68c1a40f54b1d3bfb60debdchttps://doi.org/10.1515/hc-2025-0184
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