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January 1, 2023Journal of Cardiovascular NursingOpen Access

Women with acute coronary syndrome were significantly more likely to present with atypical symptoms such as nausea (75.8% vs 48.0%) and be diagnosed with non-ST-segment elevation myocardial infarction compared to men.

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Why the study?

The study was conducted to determine gender differences in symptoms, treatment, and behaviors among individuals presenting with ACS.

Population

366 conscious/orientated patients hospitalized in a cardiology intensive care unit with ACS

Comparison

Women vs men

Design

Comparative, cross-sectional study

Key result

Women with acute coronary syndrome were significantly more likely to present with atypical symptoms such as nausea (75.8% vs 48.0%) and be diagnosed with non-ST-segment elevation myocardial infarction compared to men.

Authors

ÖCÖzlem Ceyhan

Discussion

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Member takes

Overview

May warrant sex-specific symptom vigilance in ACS evaluation; extends observational sex differences but leaves clinical impact open.

Study Design

Type

Cross-Sectional (n=366)

Multicenter

No

Structured PICO

P
Population
366 conscious and oriented patients hospitalized with acute coronary syndrome in a Turkish university hospital intensive care unit.
O
Outcome
Gender differences in symptoms, treatment, and behaviors in individuals presenting with acute coronary syndrome

Main Result

Absolute Event Rate: 75.8% vs 48%

p-value: p=<0.001

Women with acute coronary syndrome present with more atypical symptoms and non-STEMI diagnoses than men, highlighting the need for gender-sensitive clinical evaluation to prevent delayed diagnosis and treatment.

Limitations

  • Single-center study design limits generalizability to other populations.
  • Cross-sectional nature prevents establishing causality.
  • Reliance on self-reported questionnaire data collected 24 hours after admission may introduce recall bias.

Cite This Study

Özlem Ceyhan (2023) conducted a cross-sectional in Acute Coronary Syndrome (n=366). Female sex vs. Male sex was evaluated on Presentation with atypical symptoms (e.g., nausea) (p=<0.001). Women with acute coronary syndrome were significantly more likely to present with atypical symptoms such as nausea (75.8% vs 48.0%) and be diagnosed with non-ST-segment elevation myocardial infarction compared to men.

synapsesocial.com/papers/6a6f2bc78031ec7bb1dba114https://doi.org/10.5543/khd.2023.85547
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex- and Gender-Related Disparities in the Management of Acute Coronary Syndrome: A Mixed-Methods Study2025 · 1 citations
  2. 2Sex Differences and Symptoms of Acute Coronary Syndrome2015 · 2 citations
  3. 3Gender differences in the presentation and management of acute coronary syndromes: a national sample of 1365 admissions2005 · 28 citations
  4. 4Seх differences in treatment of acute coronary syndrome patients. Data from federal registry of acute coronary syndrome 2016–20192022 · 3 citations
  5. 5Gender Differences in Treatment Delays, Management and Mortalityamong Patients with Acute Coronary Syndrome: A Systematic Review andMeta-analysis2022 · 29 citations