What is the clinical evidence from this study?

Study design: Cohort. Population: Atrial fibrillation (n=10121). Intervention: Job strain. Primary outcome: Incident atrial fibrillation (HR 1.93, 95% CI 1.10-3.36).

What question did this study set out to answer?

To evaluate the association between work-related stress, defined as job strain, and the risk of developing incident atrial fibrillation.

January 1, 2015BioMed Research InternationalOpen Access

The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study

View Full Paper

Ask AI

Bookmark

Key result

Job strain was associated with an increased risk of incident atrial fibrillation, with a stronger association after 10.7 years of follow-up (HR 1.93; 95% CI 1.10-3.36).

Why the study?

Does job strain increase the risk of incident atrial fibrillation in working adults?

Population

10,121 working men and women from the Swedish WOLF study

Comparison

Job strain vs No or lower job strain

Design

Cohort

Follow-up

132,387 person-years total

Authors

EFEleonor I. FranssonJönköping University MSMagdalena StadinUppsala University MNMaria NordinUniversiti Malaysia Terengganu

Discussion

Member takes

Implication

Does not support practice change; hypothesis-generating for occupational stress as modifiable AF risk factor.

Key Points

To evaluate the association between work-related stress, defined as job strain, and the risk of developing incident atrial fibrillation.
Analyzed prospective cohort data from N=10,121 working men and women in the Swedish WOLF study followed for 132,387 person-years.
Assessed job strain using the demand-control model and identified incident atrial fibrillation cases via national health registries.
Estimated hazard ratios and 95% confidence intervals using Cox proportional hazards regression models across follow-up periods.
Identified 253 incident cases of atrial fibrillation during 132,387 person-years of follow-up.
Observed a time-dependent association with atrial fibrillation, showing a stronger risk elevation after 10.7 years of follow-up (HR 1.93, 95% CI 1.10–3.36) compared to earlier follow-up (HR 1.11, 95% CI 0.67–1.83).
Demonstrated a potential dose-response relationship when accounting for cumulative, long-term exposure to job strain.

Study Design

Type

Cohort (n=10,121)

Structured PICO

Does job strain increase the risk of incident atrial fibrillation in working adults?

Population

10,121 working men and women from the Swedish WOLF study followed for a total of 132,387 person-years to assess incident atrial fibrillation.

Exposure

Job strain (work-related stress measured by the demand-control model)

Comparator

No or lower job strain

Outcome

Incident atrial fibrillation (AF)hard clinical

Main Result

Hazard Ratio: 1.93 (95% CI 1.1–3.36)

Work-related stress, defined as job strain, is associated with a significantly increased long-term risk of developing atrial fibrillation.

Cite This Study

Fransson et al. (2015) conducted a cohort in Atrial fibrillation (n=10,121). Job strain was evaluated on Incident atrial fibrillation (HR 1.93, 95% CI 1.10-3.36). Job strain was associated with an increased risk of incident atrial fibrillation, with a stronger association after 10.7 years of follow-up (HR 1.93; 95% CI 1.10-3.36).

synapsesocial.com/papers/6a6f2beea528af2d65c2dc31 https://doi.org/10.1155/2015/371905

Topics

Atrial fibrillation Persistent AF management

View Full Paper

Ask AI

Bookmark

The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Topics

The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Topics

Also Consider