Key result
While weight loss is generally suggested to be associated with improvements in endothelial function, the published literature provides inconsistent and less than convincing evidence for its effects on endothelial activation.
Why the study?
Do weight loss interventions improve endothelial function in individuals with obesity?
Do weight loss interventions improve endothelial function in individuals with obesity?
Current evidence is unconvincing regarding the ability of weight loss interventions to significantly improve endothelial activation, despite visceral adiposity being a strong predictor of endothelial dysfunction.
Authors
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Weight loss should not yet be endorsed to improve endothelial activation in obesity; leaves open the need for rigorous RCTs.
Kerr et al. (2011) conducted a review in Obesity and endothelial dysfunction. Weight loss interventions was evaluated on Endothelial function and activation. While weight loss is generally suggested to be associated with improvements in endothelial function, the published literature provides inconsistent and less than convincing evidence for its effects on endothelial activation.
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