Key result
An intraoperative decrease in mean arterial pressure of ≥10 mm Hg was associated with a 4.1-fold higher likelihood of bilateral watershed infarcts compared to other infarct patterns.
Why the study?
Does an intraoperative drop in mean arterial pressure increase the risk of bilateral watershed infarcts, and how do these infarcts affect short-term outcomes in patients after cardiac surgery?
Population
98 patients with clinical stroke after cardiac surgery who underwent MRI with diffusion-weighted imaging…
Comparison
Intraoperative decrease in mean arterial… vs Patients without a significant intraoperative…
Design
Cohort
Follow-up
short-term (until hospital discharge)
Authors
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May not yet warrant BP target changes in cardiac surgery; hypothesis-generating for trials on MAP and watershed infarct prevention.
Observational (n=98)
Does an intraoperative drop in mean arterial pressure increase the risk of bilateral watershed infarcts, and how do these infarcts affect short-term outcomes in patients after cardiac surgery?
Odds Ratio: 4.1
Intraoperative blood pressure drops of ≥10 mm Hg during cardiac surgery are strongly associated with bilateral watershed strokes, which are best detected by MRI and carry a significantly higher risk of mortality and severe disability.
Gottesman et al. (2006) conducted an observational in Clinical stroke after cardiac surgery (n=98). Intraoperative decrease in mean arterial pressure of ≥10 mm Hg vs. No decrease in mean arterial pressure of ≥10 mm Hg was evaluated on Bilateral watershed infarcts (OR 4.1). An intraoperative decrease in mean arterial pressure of ≥10 mm Hg was associated with a 4.1-fold higher likelihood of bilateral watershed infarcts compared to other infarct patterns.
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