Key result
Impaired kidney function is linked to higher stroke risk, but not dementia.
Cohort (n=5,993)
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Longitudinal population-based data on effects of kidney dysfunction in the development of stroke and dementia remains inconclusive. We investigated associations of kidney function with risk of stroke and dementia in 5,993 community-dwelling individuals (mean age: 69.0 years, 57.2% women). We calculated estimated glomerular filtration rates based on creatinine, cystatin-C, and a combination of these two. During a mean follow-up of 11.6 years (69,790 person-years), 1,360 individuals suffered a stroke (n = 601) or developed dementia (n = 759). We found that an impaired kidney function was related to a higher risk of stroke, but not to dementia.
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Koop‐Nieuwelink et al. (2019) conducted a cohort in Community-dwelling individuals (n=5,993). Impaired kidney function vs. Normal kidney function was evaluated on Stroke and dementia. Impaired kidney function was associated with a higher risk of stroke (601 total events) but not dementia (759 total events) among 5,993 individuals followed for 11.6 years.
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