What question did this study set out to answer?

To evaluate the real-world 5-year prognosis and clinical characteristics of patients clinically diagnosed with chronic obstructive pulmonary disease (COPD) in clinical practice.

November 6, 2024BMC Pulmonary MedicineOpen Access

Update of prognosis and characteristics of chronic obstructive pulmonary disease in a real-world setting: a 5-year follow-up analysis of a multi-institutional registry

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Authors

TTTomotsugu TakanoKyushu University KTKazuya TsubouchiKyushu University NHNaoki HamadaFukuoka University Hospital

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Implication

Prospective cohort study reports an 85.4% five-year survival rate in real-world chronic obstructive pulmonary disease, highlighting poor outcomes even without airflow limitation.

Key Points

To evaluate the real-world 5-year prognosis and clinical characteristics of patients clinically diagnosed with chronic obstructive pulmonary disease (COPD) in clinical practice.
Conducted a prospective cohort study across 29 Japanese medical facilities enrolling 427 patients clinically diagnosed with COPD between September 2013 and April 2016, excluding interstitial pneumonia.
Followed patients for up to 5 years, tracking spirometric airflow limitation (AFL) by % forced expiratory volume in 1 second (FEV1) and all-cause mortality over 1,576.6 person-years.
In patients with airflow limitation (n = 374), 49 died, resulting in an overall 5-year survival rate of 85.4%.
Five-year survival decreased with advancing obstruction: 93.6% in mild/moderate AFL, 82.5% in severe AFL, and 66.1% in very severe AFL.
Patients diagnosed with COPD who lacked airflow limitation at baseline (n = 53; 12.4%) experienced a 5-year survival rate of 81.6%, presenting with respiratory symptoms, emphysematous changes, and reduced vital capacity.

Cite This Study

Takano et al. (2024) studied this question.

synapsesocial.com/papers/6a6f31cba528af2d65c2dfa6 https://doi.org/10.1186/s12890-024-03347-5

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Implication

Prospective cohort study reports an 85.4% five-year survival rate in real-world chronic obstructive pulmonary disease, highlighting poor outcomes even without airflow limitation.

Update of prognosis and characteristics of chronic obstructive pulmonary disease in a real-world setting: a 5-year follow-up analysis of a multi-institutional registry

Discussion

Member takes

Implication

Key Points

Cite This Study

Update of prognosis and characteristics of chronic obstructive pulmonary disease in a real-world setting: a 5-year follow-up analysis of a multi-institutional registry

Discussion

Member takes

Implication

Key Points

Cite This Study

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