Key result
Dietary flavonoids may aid cardiovascular prevention by reducing oxidative stress and boosting nitric oxide bioavailability.
Oxidative stress results from an imbalance between excessive formation of reactive oxygen species (ROS) and/or reactive nitrogen species and limited antioxidant defences. Endothelium and nitric oxide (NO) are key regulators of vascular health. NO bioavailability is modulated by ROS that degrade NO, uncouple NO synthase, and inhibit synthesis. Cardiovascular risk conditions contribute to oxidative stress, causing an imbalance between NO and ROS, with a relative decrease in NO bioavailability. Dietary flavonoids represent a range of polyphenolic compounds naturally occurring in plant foods. Flavonoids are potentially involved in cardiovascular prevention mainly by decreasing oxidative stress and increasing NO bioavailability.
No takes yet. Share an insight, caveat, or question.
Grassi et al. (2010) conducted a review in Atherosclerosis and cardiovascular risk. Dietary flavonoids was evaluated. Dietary flavonoids may aid in cardiovascular prevention by decreasing oxidative stress and increasing nitric oxide bioavailability.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: