Theoretical framework models interconnected neural and bodily systems in neurological disorders, suggesting integrated multi-level strategies to reduce impairment.
From a systems biology perspective, the brain and spinal cord are interwoven with the body: they are ‘embodied’. Freund et al. propose an integrative framework based on biophysical models that aims to characterize neurological disorders and minimize their impact on patients by considering functional interactions between supra-spinal, spinal and peripheral regions simultaneously.
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Freund et al. (2016) studied this question.
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