Key result
A single hemodialysis session significantly reduced left ventricular average energy loss in the early diastolic phase from 29.43 to 17.70 N/(m2·s) (P<0.001) in patients with end-stage renal disease.
Why the study?
The influence of hemodialysis on left ventricular hydromechanics had not been reported.
Does a single hemodialysis session reduce left ventricular energy loss and wall shear stress in patients with end-stage renal disease?
Observational (n=40)
No
Does a single hemodialysis session reduce left ventricular energy loss and wall shear stress in patients with end-stage renal disease?
A single hemodialysis session significantly reduces left ventricular energy loss and wall shear stress during the systolic and diastolic phases, reflecting changes in fluid load and hemodynamics in patients with uremic cardiomyopathy.
Background: The influence of hemodialysis (HD) on hydromechanics of the left ventricle has not been reported. This study evaluated the left ventricular summation of energy loss (EL-SUM), average energy loss (EL-AVE), and wall shear stress (WSS) before and after HD using vector flow mapping (VFM) in patients with end-stage renal disease (ESRD). Methods: We prospectively recruited 40 patients receiving long-term HD and excluded those with structural cardiac disease. Echocardiography was performed before and within 24 hours after HD. Conventional echocardiographic parameters, summation, and average energy loss (EL-SUM, EL-AVE, EL-base, EL-mid and EL-apex), and WSS in each segment were compared. Results: 0.57 (0.42 to 0.68) Pa, P=0.029] phases. There was no change in WSS during the early diastolic, late diastolic, and late systolic phases. Conclusions: After HD, EL and WSS of LV decrease during the systolic and diastolic phases. The VFM can reflect the LV hemodynamics in patients undergoing HD under different fluid loads.
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Hong et al. (2022) conducted an observational in End-stage renal disease (ESRD) (n=40). Single hemodialysis vs. Before hemodialysis was evaluated on Left ventricular average energy loss (EL-AVE) in the early diastolic phase (p=<0.001). A single hemodialysis session significantly reduced left ventricular average energy loss in the early diastolic phase from 29.43 to 17.70 N/(m2·s) (P<0.001) in patients with end-stage renal disease.
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