Key result
A single hemodialysis session significantly worsened left ventricular global longitudinal strain from -14.2 to -11.1 (P<0.001), with no significant changes in right ventricular strain.
Why the study?
The effects of acute changes during hemodialysis on the myocardium were not yet known.
Does a standard hemodialysis session acutely impair myocardial performance assessed by 3DSTE in patients with normal LVEF?
Population
38 maintenance hemodialysis patients with normal LVEF and no known cardiovascular disease
Comparison
Just before vs after a hemodialysis session
Design
Observational cohort study
Authors
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Acute LV strain decline after hemodialysis may indicate stunning in preserved EF; leaves open its contribution to long-term CV risk in dialysis patients.
Observational (n=38)
No
Does a standard hemodialysis session acutely impair myocardial performance assessed by 3DSTE in patients with normal LVEF?
Absolute Event Rate: -11.1% vs -14.2%
p-value: p=<.001
Standard hemodialysis acutely impairs left ventricular global and regional strain in patients with normal ejection fraction, suggesting a stunning effect that may contribute to cardiovascular risk.
Güler et al. (2020) conducted an observational in Maintenance hemodialysis (n=38). Hemodialysis session vs. Before hemodialysis (baseline) was evaluated on Left ventricular global longitudinal strain (GLS) (p=<.001). A single hemodialysis session significantly worsened left ventricular global longitudinal strain from -14.2 to -11.1 (P<0.001), with no significant changes in right ventricular strain.
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