Key result
A single hemodialysis session is linked to a ~2.4% worsening of GLS in pediatric patients.
Why the study?
Children on long-term hemodialysis experience reduced life expectancy primarily from cardiovascular mortality, but the effects of hemodialysis on cardiac function in pediatric populations have not been fully elucidated.
Does a single hemodialysis session alter echocardiographic parameters of cardiac function in pediatric patients with end-stage renal disease?
Population
23 pediatric patients with ESRD on maintenance hemodialysis
Comparison
Echocardiographic parameters before vs after a single hemodialysis session
Design
Prospective comparative study
Follow-up
30-60 minutes after hemodialysis
Authors
Loading...
GLS deterioration after hemodialysis in pediatric ESRD may signal subclinical dysfunction missed by ejection fraction; leaves open need for outcome studies before guiding monitoring.
Observational (n=23)
No
Does a single hemodialysis session alter echocardiographic parameters of cardiac function in pediatric patients with end-stage renal disease?
Mean Difference: 2.4
Absolute Event Rate: -14.9% vs -17.3%
p-value: p=4.10-8
Speckle tracking echocardiography reveals significant deterioration in left ventricular global longitudinal strain following a hemodialysis session in pediatric patients with ESRD, despite preserved conventional ejection fraction.
Boudiche et al. (2024) conducted an observational in End-stage renal disease (n=23). Hemodialysis session vs. Pre-hemodialysis was evaluated on Left ventricular global longitudinal strain (GLS) (MD 2.4%, p=4.10-8). A single hemodialysis session significantly worsened left ventricular global longitudinal strain from -17.3% to -14.9% (p=4.10-8) in pediatric patients with end-stage renal disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: