Key result
Subclinical hypothyroidism was associated with prolonged myocardial precontraction time, precontraction/contraction time ratio, and relaxation time compared to healthy women.
Why the study?
Does subclinical hypothyroidism impair left ventricular myocardial regional function as assessed by pulsed tissue Doppler in women?
Case-Control (n=40)
Does subclinical hypothyroidism impair left ventricular myocardial regional function as assessed by pulsed tissue Doppler in women?
Pulsed tissue Doppler echocardiography can detect early left ventricular functional abnormalities, specifically prolonged myocardial time intervals, in patients with stable subclinical hypothyroidism.
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Supports early LV assessment by tissue Doppler in subclinical hypothyroidism; leaves open clinical relevance and need for prospective trials.
Vitale et al. (2002) conducted a case-control in Subclinical hypothyroidism (n=40). Subclinical hypothyroidism vs. Healthy women was evaluated on Left ventricular myocardial regional function (myocardial systolic and diastolic velocities and time intervals). Subclinical hypothyroidism was associated with prolonged myocardial precontraction time, precontraction/contraction time ratio, and relaxation time compared to healthy women.
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