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July 1, 1995Journal of Clinical InvestigationOpen Access

Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.

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Authors

YMYoshikazu MiyazakiUniversity of GenevaKAKimi ArakiKumamoto Health Science UniversityCVChristian VesinUniversity of Geneva

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Miyazaki et al. (1995) studied this question.

synapsesocial.com/papers/6a6f3339f44fa9f079dc9cbehttps://doi.org/10.1172/jci118029
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis1987 · 417 citations
  2. 2Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro1985 · 1,596 citations
  3. 3Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect.1992 · 70 citations
  4. 4Expression of tumour necrosis factor‐α in cryptogenic fibrosing alveolitis1993 · 76 citations