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June 26, 2009Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Effects of Pharmacist Participation in Intensive Care Units on Clinical and Economic Outcomes of Critically Ill Patients with Thromboembolic or Infarction‐Related Events

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Why the study?

Does clinical pharmacist participation in the ICU improve clinical and economic outcomes in critically ill Medicare patients with thromboembolic or infarction-related events?

Population

141,079 critically ill Medicare patients with thromboembolic or infarction-related events, of whom 7,987 had…

Comparison

Clinical pharmacy services. vs ICUs without clinical pharmacy services.

Design

Cohort

Follow-up

Duration of ICU stay

Authors

RMRobert MacLarenAmerican Association of Colleges of PharmacyCBChristopher BondNorthwestern University

Discussion

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Implication

May support pharmacist integration in ICU thromboembolic care; observational design leaves causal benefit open for RCTs.

Structured PICO

Does clinical pharmacist participation in the ICU improve clinical and economic outcomes in critically ill Medicare patients with thromboembolic or infarction-related events?

P
Population
141,079 critically ill Medicare patients with thromboembolic or infarction-related events (TIE), of whom 7,987 had bleeding complications.
I
Intervention
Clinical pharmacy services (direct patient care services provided by a pharmacist specifically devoted to the ICU).
C
Comparator
ICUs without clinical pharmacy services.
O
Outcome
Mortality rates, length of intensive care unit (ICU) stay, total Medicare charges, drug and laboratory charges, and rates of bleeding complications.hard clinical

Involving clinical pharmacists in the direct care of ICU patients with thromboembolic or infarction-related events is associated with reduced mortality, improved clinical and economic outcomes, and fewer bleeding complications.

Cite This Study

MacLaren et al. (2009) studied this question.

synapsesocial.com/papers/6a6f342e2163a0a01bc3890dhttps://doi.org/10.1592/phco.29.7.761
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