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January 1, 1993European Journal of Cardio-Thoracic Surgery

Troponin T — a reliable marker of perioperative myocardial infarction?

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Why the study?

Does serial measurement of troponin T reliably diagnose perioperative myocardial infarction in patients undergoing myocardial revascularization?

Population

90 patients with severe diffuse three-vessel disease undergoing myocardial revascularization.

Comparison

Serial measurement of troponin T levels at 6… vs Serial measurement of CK-MB activity and…

Design

Cohort

Follow-up

48 hours

Authors

UHU. HakeKlinik für Herzchirurgie KarlsruheFSFranz‐Xaver SchmidHelios Klinikum KrefeldSIStein IversenHelios Hospital Siegburg

Discussion

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Member takes

Implication

Troponin T elevation was associated with perioperative MI by ECG and CK-MB criteria; leaves open its reliability as a diagnostic marker after revascularization.

Structured PICO

Does serial measurement of troponin T reliably diagnose perioperative myocardial infarction in patients undergoing myocardial revascularization?

P
Population
90 patients with severe diffuse three-vessel disease undergoing myocardial revascularization.
I
Intervention
Serial measurement of troponin T levels at 6, 12, 24, and 48 hours after aortic unclamping.
C
Comparator
Serial measurement of CK-MB activity and postoperative electrocardiographic (ECG) findings.
O
Outcome
Diagnosis of perioperative myocardial infarction based on troponin T levels compared to CK-MB and ECG findings.surrogate

Troponin T is a reliable marker for diagnosing perioperative myocardial infarction following cardiac surgery, with a single value at 6 or 24 hours potentially sufficient for confirmation.

Cite This Study

Hake et al. (1993) studied this question.

synapsesocial.com/papers/6a6f350cac440176ef27ea5ahttps://doi.org/10.1016/1010-7940(93)90256-b
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1S-troponin T in suspected ischemic myocardial injury compared with mass and catalytic concentrations of S-creatine kinase isoenzyme MB1991 · 281 citations
  2. 2New bundle branch block after coronary artery bypass grafting— evaluation by CK-MB isoenzyme analysis and transoesophageal echocardiography1990 · 8 citations
  3. 3Monoclonal antibodies specific for human cardiac myosin: selection, characterization and experimental myocardial infarct imaging1988 · 8 citations
  4. 4Western Washington Randomized Trial of Intracoronary Streptokinase in Acute Myocardial Infarction1983 · 788 citations
  5. 5Serum protein measurements and the diagnosis of acute myocardial infarction.1991 · 43 citations