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July 1, 1948The Journal of Experimental MedicineOpen Access

The Rate of Bactericidal Action of Penicillin in Vitro as a Function of Its Concentration, and Its Paradoxically Reduced Activity at High Concentrations Against Certain Organisms

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Authors

HEHarry EaglePeterborough City HospitalAMArlyne D. MusselmanNational Institutes of Health

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Eagle et al. (1948) studied this question.

synapsesocial.com/papers/6a6f358aa7fbea1e4407b0fahttps://doi.org/10.1084/jem.88.1.99
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE SPIROCHETICIDAL ACTION OF PENICILLIN IN VITRO AND ITS TEMPERATURE COEFFICIENT1944 · 49 citations
  2. 2Production of Staphylococcus Strains Resistant to Various Concentrations of Penicillin1945 · 224 citations