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June 1, 1974Journal of Neurology Neurosurgery & PsychiatryOpen Access

Electrocardiographic changes and their prognostic significance in subarachnoid haemorrhage

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Why the study?

Do specific catecholamine-linked ECG changes predict poor prognosis (death or cerebral arterial spasm) in patients with subarachnoid haemorrhage?

Population

40 patients with subarachnoid haemorrhage (16 men, mean age 41 years; 24 women, mean age 42 years)

Comparison

Presence of catecholamine-linked ECG changes vs Absence of these specific ECG changes

Design

Cohort

Authors

JCJ. M. CruickshankAstraZeneca (United Kingdom)GNG. Neil‐DwyerEssex Cardiothoracic CentreJBJason BriceSt George's Hospital

Discussion

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Implication

ECG abnormalities were associated with death and vasospasm in SAH; hypothesis-generating and requires prospective validation before guiding care.

Structured PICO

Do specific catecholamine-linked ECG changes predict poor prognosis (death or cerebral arterial spasm) in patients with subarachnoid haemorrhage?

P
Population
40 patients with subarachnoid haemorrhage (16 men, mean age 41 years; 24 women, mean age 42 years)
I
Intervention
Presence of catecholamine-linked ECG changes (pathological Q waves, raised S-T segments, peaked P waves, short P-R intervals, long Q-Tc, tall U waves)
C
Comparator
Absence of these specific ECG changes
O
Outcome
Death and development of cerebral arterial spasmhard clinical

Specific ECG abnormalities, such as pathological Q waves and raised S-T segments, are associated with a poor prognosis and the development of cerebral arterial spasm in patients with subarachnoid haemorrhage.

Cite This Study

Cruickshank et al. (1974) studied this question.

synapsesocial.com/papers/6a6f36d5e5469ee92be03ea3https://doi.org/10.1136/jnnp.37.6.755
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Also Consider

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  1. 1Electrocardiographic Observations and Urinary Excretion of Catecholamines in Cerebrovascular Accidents1964 · 36 citations
  2. 2Electrocardiographic Changes in Head Injuries1961 · 124 citations
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  5. 5Study of Atrioventricular Conduction in Man Using Electrode Catheter Recordings of His Bundle Activity1969 · 172 citations