Key result
Multipolar mapping and catheter ablation of papillary muscle premature ventricular complexes using a duodecapolar catheter achieved a 100% acute success rate and significantly reduced PVC burden from 16.2% to 0.7% (P=0.001).
Why the study?
Catheter ablation of LV papillary muscle PVCs previously showed modest procedural success and high recurrence rates, prompting evaluation of multipolar mapping with a steerable linear duodecapolar catheter.
Does multipolar mapping with a duodecapolar catheter improve ablation success for papillary muscle PVCs in patients with structurally normal hearts?
Does multipolar mapping with a duodecapolar catheter improve ablation success for papillary muscle PVCs in patients with structurally normal hearts?
Absolute Event Rate: 0.7% vs 16.2%
p-value: p=0.001
Multipolar mapping with a linear duodecapolar catheter is feasible and highly efficient for guiding catheter ablation of papillary muscle PVCs, resulting in high acute success and low recurrence.
May inform ablation strategies for papillary muscle PVCs; hypothesis-generating and should not yet change practice.
BACKGROUND: Previous studies on radiofrequency catheter ablation of premature ventricular complexes (PVCs) arising from the left ventricle (LV) papillary muscles (PM) show a modest procedural success rate with higher recurrence rate. Our study sought to explore the utility of using a multipolar mapping with a steerable linear duodecapolar catheter for ablating the PM PVCs. METHODS: Detailed endocardial multipolar mapping was performed using a steerable linear duodecapolar catheter in 6 consecutive PM PVCs patients with structurally normal heart. The clinical features and procedural data as well as success rate were analysed. RESULTS: LV endocardial electroanatomic mapping was performed in all patients via a retrograde aortic approach using a duodecapolar mapping catheter. All patients displayed a PVC burden with 16.2 ± 5.4%. Duodecapolar catheter mapping demonstrated highly efficiency with an average procedure time (95.8 ± 7.4 min) and fluoroscopy time (14.2 ± 1.5 min). The mean number of ablation applications points was 6.8 ± 1.9 with an average overall ablation duration of 6.1 ± 3.0 min. The values of earliest activation time during mapping using duodecapolar catheter were 37.8 ± 7.2 ms. All patients demonstrated acute successful ablation, and the PVC burden in all patients after an average follow-up of 8.5 ± 2.0 months was only 0.7%. There were no complications during the procedures and after follow-up. CONCLUSIONS: Mapping and ablation of PM PVCs using a duodecapolar catheter facilitated the identification of earliest activation potentials and pace mapping, and demonstrated a high success rate during follow-up.
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Cai et al. (2020) studied Premature ventricular complexes originating from papillary muscles (n=6). Multipolar mapping and catheter ablation using a duodecapolar catheter was evaluated on Premature ventricular complex (PVC) burden (p=0.001). Multipolar mapping and catheter ablation of papillary muscle premature ventricular complexes using a duodecapolar catheter achieved a 100% acute success rate and significantly reduced PVC burden from 16.2% to 0.7% (P=0.001).
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