Why the study?
Does atorvastatin 10 mg daily improve regional arterial stiffness in patients with type 2 diabetes mellitus and hypercholesterolemia?
Does atorvastatin 10 mg daily improve regional arterial stiffness in patients with type 2 diabetes mellitus and hypercholesterolemia?
Atorvastatin 10 mg daily for 6 months significantly reduces femoral-ankle arterial stiffness in patients with type 2 diabetes, providing a potential mechanism for statin-mediated improvements in walking performance for patients with peripheral arterial disease.
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Atorvastatin was associated with reduced femoral-ankle PWV in T2DM; hypothesis-generating for PAD benefits, needs RCTs before practice change.
Shinohara et al. (2005) studied this question.
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