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October 1, 1973The Journal of ImmunologyOpen Access

Purification of Mouse Interferon by Affinity Chromatography on Anti-Interferon Globulin-Sepharose

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Population

Mouse interferon produced in L cells

Design

Preclinical

Authors

COClifton A. OgburnUniversity of the SciencesKBKurt BergThe University of Texas Health Science Center at San AntonioKPKurt PauckerShriners Hospitals for Children - Galveston

Discussion

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Overview

Affinity chromatography enables quantitative mouse interferon purification; leaves open translation to other species or clinical use.

Structured PICO

P
Population
Mouse interferon produced in L cells
I
Intervention
Affinity chromatography on Sepharose-bound anti-interferon globulin
O
Outcome
Recovery of interferon and purification foldsurrogate

Affinity chromatography using Sepharose-bound anti-interferon globulin is an effective method for the selective purification and quantitative recovery of mouse interferon.

Cite This Study

Ogburn et al. (1973) studied this question.

synapsesocial.com/papers/6a6f3cb535aa2c282ce0a270https://doi.org/10.4049/jimmunol.111.4.1206
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Also Consider

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  5. 5Interferon Synthesis in X-Irradiated Animals V. Origin of Mouse Serum Interferon Induced by Polyinosinic-Polycytidylic Acid and Encephalomyocarditis Virus1974 · 20 citations