Key result
Five weeks of aerobic treadmill training in rats significantly increased the running speed at lactate threshold from 26.21 to 35.30 m/min and reduced blood lactate concentration at the threshold.
Why the study?
Does a 5-week aerobic treadmill training program improve lactate threshold in rats?
Does a 5-week aerobic treadmill training program improve lactate threshold in rats?
Absolute Event Rate: 35.3% vs 20.15%
p-value: p=0.004
A 5-week aerobic treadmill training program in rats induces positive oxidative physiological adaptations, significantly increasing the running speed at the lactate threshold and reducing blood lactate levels.
Hypothesis-generating in rat models; leaves open translation to human cardiovascular training.
The aim of the present study was to analyse the lactate threshold (LT) changes in rats submitted to an aerobic treadmill-training programme. Twenty-five Wistar rats were divided into two groups: a sedentary control group (CG), and a trained group (TG) submitted to an aerobic training during 5 weeks. All the animals were submitted to an incremental treadmill exercise test in order to determine LT. There was an increase in the maximum running speed in the TG (from 32.25 ± 1.27 to 47.75 ± 3.13 m.min-1 - p = 0.001), and running speed at LT (from 26.21 ± 1.15 to 35.30 ± 2.24 m.min-1 - p = 0.004), a part from the reduction in blood lactate at LT. LT can be determined in rats, and aerobic training induced positive oxidative physiological adaptations in the animals.
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Vieira et al. (2014) studied Healthy (Wistar rats) (n=25). Aerobic treadmill training vs. Sedentary control was evaluated on Running speed at lactate threshold (LT) (p=0.004). Five weeks of aerobic treadmill training in rats significantly increased the running speed at lactate threshold from 26.21 to 35.30 m/min and reduced blood lactate concentration at the threshold.
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